A single fecal microbiota transplant (FMT) appeared to reprogram the gut microbiomes of advanced melanoma patients to overcome their primary resistance to anti-programmed cell death protein 1 (PD-1) immunotherapy, a small single-arm phase II trial found.
Publications
Clinical features of subungual melanoma according to the extent of Hutchinson’s nail sign: A retrospective single-centre study
Researchers sought to determine clinicopathological characteristics of subungual melanoma (SUM) according to the extent of Hutchinson’s nail sign (HS).
The predictive and prognostic significance of cell?free DNA concentration in melanoma
In this study with a discovery cohort (n = 20) and expansion cohort (n = 166) comprising metastatic melanoma cases and healthy donors (n = 116), researchers examined the link between circulating cell?free DNA (cfDNA) and potential confounders and assessed the monitoring value of total cfDNA level during treatment…
Melanoma breakthrough: New treatment saving lives
In what is being hailed as one of the biggest breakthroughs in melanoma treatment since the advent of immunotherapy, a new study has revealed that drug treatment before surgery is effective in preventing deadly spread of the disease.