In acral melanoma (AM) cases, ulceration was identified to be an independent negative prognostic factor but the impact differed across Breslow thicknesses and clinical stages.
Skin cancer is the most common type of cancer in Brazil, accounting for 33% of cases in the country. The National Cancer Institute (Inca) records about 185 thousand new diagnoses of the disease annually, and melanoma is considered the most aggressive form of the disease, responsible for more than 8 thousand cases.
Discovering new bait for the immune system may lead to additional treatments for melanoma. Congratulations Andreas Behren, Katherine Woods, Jonathan Cebon, Stephen Wong and colleagues
A collaborative study, led by ONJCRI and the Monash Biomedicine Discovery Institute (BDI) at Monash University, has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.