Of Interest

Dr Pavlick on RP1 Plus Nivolumab in PD-1 Inhibitor–Pretreated Melanoma

Anna C. Pavlick, BSN, MSc, DO, MBA, a professor of medicine in the Division of Hematology & Medical Oncology at Weill Cornell Medicine; as well as the founding director of the Cutaneous Oncology Program at Weill Cornell Medicine and NewYork-Presbyterian, discussed key findings from the phase 2 IGNYTE trial (NCT03767348) investigating the efficacy and safety of RP1 plus nivolumab (Opdivo) in patients with melanoma who had progressed on prior PD-1–directed therapy.

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Mount Sinai Researchers Discover How Melanoma May Spread to the Brain

Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in the latest issue of Molecular Cell, highlights the role of a group of proteins called the PBAF chromatin remodeling complex in keeping melanoma from getting worse.

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