Fecal microbiota transplants help patients with advanced melanoma respond to immunotherapy

Source: Science Daily, February 2021

For patients with cancers that do not respond to immunotherapy drugs, adjusting the composition of microorganisms in the intestines — known as the gut microbiome — through the use of stool, or fecal, transplants may help some of these individuals respond to the immunotherapy drugs, a new study suggests.

Researchers at the National Cancer Institute (NCI) Center for Cancer Research, part of the National Institutes of Health, conducted the study in collaboration with investigators from UPMC Hillman Cancer Center at the University of Pittsburgh.

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