Archive | Scientific Publications

Effect of cyclo-oxygenase inhibitor use during checkpoint blockade immunotherapy in patients with metastatic melanoma and non-small cell lung cancer

Immune checkpoint inhibitors (ICIs) improve survival outcomes in metastatic melanoma and non-small cell lung cancer (NSCLC).

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The prognostic significance of non-sentinel lymph node metastasis in cutaneous and acral melanoma patients-A multicenter retrospective study

Whether non-sentinel lymph node (SLN)-positive melanoma patients can benefit from completion lymph node dissection (CLND) is still unclear.

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Does very early timing of lymph node surgery after resection of the primary tumour improve the clinical outcome of patients with melanoma?

Researchers investigated if the clinical outcome of patients with cutaneous melanoma could be impacted by very early timing of sentinel lymph node biopsy (SLNB) post-resection of the primary tumour, or by timing of complete lymph node dissection (CLND) following SLNB, vs longer time intervals. Experts analyzed a cohort comprising 896 patients with melanoma who had […]

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What is the accuracy of reflectance confocal microscopy (RCM) for the diagnosis of cutaneous malignant melanoma (MM) or melanoma in situ (MiS) in adults?

Source: Cochrane Library, September 2020 Reviewers identified eight studies (9 evaluations, 1452 lesions, 370 cases of MM/MiS) that assessed the diagnostic accuracy of RCM, most commonly using histology as the reference standard (one study used unequivocal clinical and conventional dermoscopic criteria, and another used clinical follow-up in most participants). Across studies, average sensitivity ranged from […]

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