Melanoma News

Mechanism of Positive Association Between Parkinson’s Disease and Melanoma Revealed in New Research

There is a positive association between melanoma and Parkinson’s disease (PD), with the risk for melanoma ranging between 1.4- and 20-fold among individuals with PD. The risk is bidirectional, too, because there is also a 1.7- to 4.2-fold increased risk for PD in patients with melanoma. The link between PD and melanoma is not well understood, but increased expression of the PD-associated protein alpha-synuclein (?Syn) in melanoma cells may provide insight into the positive association between the two diseases.

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