Activation of the PI3K/AKT pathway may play a role in the development of metastases in melanoma, according to a preclinical study published in Cell Report.1
Cancer risk increases with one’s age as accumulated damage to our cells and chronic inflammation occur over time. Now, an international team of scientists led by The Wistar Institute have shown that aged tumor cells in melanoma behave differently than younger tumor cells, according to study results published in the journal Nature.
In a new study, researchers investigated whether molecular profiling could predict clinical outcomes, and found that patients with primary malignant melanoma are at a higher risk of recurrent disease if they present mutations in two or more cancer-related genes. The study’s results were recently presented at the 2016 HemOnc Today Melanoma and Cutaneous Malignancies meeting.
