Scientific Publications

As per experimental evidence, dietary intakes of omega-3 and omega-6 polyunsaturated fatty acids (FAs) have divergent effects on melanoma growth, researchers here sought for epidemiologic evidence on their combined effect.

Please click on the link to see a list of melanoma journal articles that came across the MRV desk recently.

Given that objective responses in 30% to 50% of patients suffering from metastatic melanoma is mediated by adoptive cell transfer (ACT) of tumor-infiltrating lymphocytes (TIL), as per multiple, small phase 2 trials, so, researchers assessed long-term clinical outcomes, intent-to-treat analysis, predictors of response as well as toxicity profile in a large patient cohort.

In the present study, the researchers sought to explore the connection between immune-related adverse events and recurrence-free survival (RFS) in the double-blind EORTC 1325/KEYNOTE-054 clinical trial comparing pembrolizumab therapy and placebo for the treatment of individuals with high-risk stage III melanoma.