To clarify the role of the AP-2alpha transcription factor, which is encoded by TFAP2A, in melanoma metastasis, researchers undertook this study.
Scientific Publications
STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
BACKGROUND: Resistance to an immune checkpoint inhibitor (ICI) is a major obstacle in cancer immunotherapy.
Complete remission in metastatic primary malignant melanoma of the esophagus with nivolumab: a case report
Primary malignant melanoma of the esophagus is a rare form of mucosal melanoma with a poor prognosis.
Bempegaldesleukin plus nivolumab in first-line metastatic melanoma
In this phase II cohort from the international, single-arm PIVOT-02 study, researchers sought to assess the CD122-preferential interleukin-2 pathway agonist bempegaldesleukin (BEMPEG) plus nivolumab (NIVO) in first-line metastatic melanoma.