This study sought to report the development and validation of a melanoma prediction model from spatially resolved multivariate protein expression profiles generated by Imaging Mass Spectrometry (IMS).
Publications
Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
Researchers sought to determine the potential mechanisms underlying melanoma metastasis.
Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma
The use of MEK inhibitors in the therapy of uveal melanoma (UM) has been investigated widely but has failed to show benefits in clinical trials due to fast acquisition of resistance.
AP-2alpha-mediated activation of E2F and EZH2 drives melanoma metastasis
To clarify the role of the AP-2alpha transcription factor, which is encoded by TFAP2A, in melanoma metastasis, researchers undertook this study.