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Scientific Journals for August 2015

Of Interest, Scientific Publications
___________________________________________________________________________________________________________________________________ Cancer Cell Herrero, A. et al. Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes. Cancer Cell 28, 170–182 (2015) ______________________________________________________________________________________________________________________________________ American Journal of Ophthalmology Secondary Enucleations for Uveal Melanoma: A…
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Researchers Identify Novel Mutation in Melanoma Cancer Cells

MRV Research, Health Professionals, Of Interest, Scientific Publications

In a recent study published in Science Signaling entitled “The E3 ligase APC/CCdh1 promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth“, scientists from the Boston University School of Medicine (BUSM) found that humans susceptible to develop melanoma cancer have lower levels of Cdh1, a tumor suppressor gene. This gene belongs to a protein complex called Anaphase-Promoting Complex (APC/C).

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