Veteran cancer reseacher Prof. Emeritus Alexander Levitzki of Hebrew University of Jerusalem says new findings show link between colorectal cancer and melanoma drug treatment knoqwn as “NT157" in two recently published studies in journal, “Ocogene."
Publications
FDA approves Cotellic as part of combination treatment for advanced melanoma
The U.S. Food and Drug Administration today approved Cotellic (cobimetinib) to be used in combination with vemurafenib to treat advanced melanoma that has spread to other parts of the body or can’t be removed by surgery, and that has a certain type of abnormal gene (BRAF V600E or V600K mutation).
Study identifies potential therapeutics target for metastatic melanoma
Researchers in the Randall Division of Cell & Molecular Biophysics have had the findings of their study into a potential therapeutics target for metastatic melanoma published in the journal Current Biology.
Exceptional Response in Brain Tumor Patient Instills Confidence in Personalized Medicine
A young man, less than 40 years old, with recurrent craniopharyngioma (pituitary tumor) harboring a BRAF V600E mutation, showed a dramatic response when treated with BRAF V600E inhibitors—85% reduction in tumor volume. This case has the “potential of completely changing the management of papillary craniopharyngiomas,” according to study author Priscilla Brastianos, MD, of the Massachusetts General Hospital (MGH) Cancer Center.