In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms, administration recommendations, safety profiles, and other essential information needed for the appropriate clinical use of these drugs
Publications
MITF gene variant associated with increased melanoma risk, high nevi count
A rare functional variant in the MITF gene was associated with increased melanoma risk, especially in patients with multiple primary melanoma, and high nevi count, according to study results recently published in JAMA Dermatology.
FDA requests more data for Opdivo in treating BRAF V600 mutation-positive melanoma
Bristol-Myers Squibb announced that the FDA has requested additional data in its response to its supplemental biologics license application for Opdivo as monotherapy for previously untreated patients with BRAF V600 mutation-positive unresectable or metastatic melanoma.
First oncolytic virus vaccine for advanced melanoma
FDA recently approved the first oncolytic virus therapy: talimogene laherparepvec (Imlygic—BioVex/Amgen), a modified live herpes simplex virus type 1 oncolytic virus therapy, for the treatment of recurrent melanoma.