MRV Research

A new take on melanoma diagnosis

Colour is an important characteristic for diagnosing skin lesions such as malignant melanoma. In dermatological images, however, the colour is affected not only by melanin and haemoglobin under the skin surface, but also by the presence of external illumination. If pigmentation data are affected by illumination artefacts, conventional colourimetry may not accurately describe the skin histology and disease may be incorrectly diagnosed.

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Optimization of Melanoma Treatment Advances Remains a Work in Progress

Immunotherapies and targeted therapies have led to significant strides in the treatment of patients with melanoma. However, determining which therapies are best for which patients and how to treat patients who don’t respond or stop responding to these new therapies is still a challenge. For further insight on optimizing the recent treatment breakthroughs in melanoma, OncLive spoke with Alan Bryce, MD, medical director of the Genomic Oncology Clinic at Mayo Clinic.

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Novel Anti-Melanoma Antibiotic-Based Strategy Identified in New Study

MRV Research

A research team at the Roswell Park Cancer Institute in Buffalo found that a previously identified antibiotic has anti-melanoma activity. The study entitled “Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity” was published in the journal Cell Death and Differentiation. This research was supported by the Jennifer Linscott Tietgen Family Foundation, which is dedicated to supporting melanoma cancer research in memory of their daughter, Jennifer.

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