A recent study led by researchers at Tel Aviv University (TAU) in Israel revealed the trigger that causes melanoma cells to transform into invasive, lethal cells. The study is entitled “Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF” and was published in the journal Molecular Cell.
MRV Research
Penn scientists identify key genetic factor that keeps moles from turning into melanoma
Moles are benign tumors found on the skin of almost every adult. Scientists have known for years that a mutation in the BRAF gene makes them start growing, but until now haven’t understood why they stop. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania have identified a major genetic factor that keeps moles in their usual non-cancerous, no-growth state. The study was published online first this summer in the journal Cancer Discovery.
Risk factors for melanoma among survivors of non-Hodgkin lymphoma
Investigators sought to quantify risks associated with specific treatments and immune-related risk factors for cutaneous melanoma among survivors of non-Hodgkin lymphoma.
Melanoma Risk Increased in CLL/SLL Patients
Results of a new study have indicated that the risk of developing melanoma may be almost doubled among survivors of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who were treated with certain chemotherapeutic agents or who had specific immune-related medical conditions.