Although many different skin reactions to melanoma drugs are labeled as a “rash," differentiating them could improve treatment. A report published online July 22 in JAMA Dermatology described the cutaneous toxicity seen with BRAF and MEK inhibitors used to treat metastatic melanoma.
MRV Research
Pembrolizumab
Along with vemurafenib1, dabrafenib2 and trametinib3, pembrolizumab is approved for metastatic melanoma. Like ipilimumab4, it is an immune checkpoint inhibitor that works by modulating the patient’s own immune response to tumour cells.5
Pregnancy Does Not Influence Melanoma Prognosis
Results from a recent study published in the journal Dermatologic Surgery have shown that women who became pregnant after being diagnosed with melanoma did not experience a significantly worse clinical prognosis.
Veterans who served in the deserts of Afghanistan and Iraq have increased risk of skin cancer
Veterans who return home from the sun-baked Middle East have an increased chance of developing potentially deadly skin cancer, a study has concluded.
The new study, published in the Journal of Investigative Dermatology, found that many soldiers in Afghanistan and Iraq who spent much of their deployments outdoors weren’t adequately trained about the dangers of sun exposure and failed to use sunscreen regularly to help prevent melanoma.