The mechanism by which benign melanoma cells change into malignant ones is greatly affected by the cells’ stiffness, as determined by the specific balance of two signaling pathways — which, in turn, can be affected by a genetic deletion, according to Yale University researchers.
MRV Research
Lower Vitamin D Levels Predict Poor Survival Outcomes in Melanoma
In patients with melanoma, lower 25-hydroxyvitamin D (vitamin D) levels were associated with poorer survival outcomes, according to a prospective study. This association was independent of C-reactive protein (CRP) levels.
Biomarker for Class 1 Uveal Melanoma Correlates with Metastatic Disease
A new biomarker measurement might improve the accuracy of prognostic testing and precision medicine in uveal melanoma, according to a study published in Clinical Cancer Research.1
Talimogene laherparepvec, pembrolizumab combination safely treats advanced melanoma
NEW YORK — Patients with advanced unresectable melanoma can safely receive combination therapy with full doses of talimogene laherparepvec and pembrolizumab, according to study results presented at HemOnc Today Melanoma and Cutaneous Malignancies.