Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in Molecular Cell, highlights the role of a group of proteins called the PBAF chromatin remodeling complex in keeping melanoma from getting worse.
Melanoma News
Genetic Ancestry of Patients With High-Risk Melanoma: Tarhini’s Insights
Researchers identified key ancestral contributions among patients with high-risk melanoma in a US intergroup phase 3 trial. Most cases genetically clustered with European reference populations, with smaller subsets aligning with admixed American and East Asian ancestries.
Immunotherapy Improves Overall Survival in Women With Genital Tract Melanoma
Overall survival (OS) in women with genital tract melanoma (GTM) is improved with immunotherapy, according to study findings published in Melanoma Research.
Exploring the Long-Term Psychosocial Impacts of Stage IV Melanoma in Survivors
Stage IV melanoma survivors face persistent adverse effects and distress, highlighting the need for targeted psychological support and care.