The growing incidence of melanoma appears to be more related to increased diagnostic scrutiny from clinicians than to increased UV radiation exposure, a new analysis suggests.
2022
Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis
A group of researchers based in Brazil and France have managed to discover markers left by exposure to sunlight in the genomes of people who suffer from cutaneous melanoma. An article about the study published in Nature Communications also offers a novel understanding of other melanomas not caused by the effects of ultraviolet (UV) radiation.
Targeted Therapy Combinations Provide Multiple Treatment Options in BRAF-Mutated Melanoma
Jeff Yorio, MD, discussed the decision-making process for treating patients with BRAF-mutant melanoma, the use of immunotherapy in melanoma, and the management of cutaneous squamous cell carcinoma and basal cell carcinoma.
Sequential Immunotherapy and Targeted Therapy Shows OS Benefit in BRAF+ Melanoma
Three different sequencing schemas for immunotherapy followed by targeted therapy in patients with BRAF V600-mutant melanoma have shown positive survival outcomes and safety consistent with results from prior studies.