Health Professionals

How melanoma and other tumors succeed in hiding and resisting immunotherapy

Cutaneous melanoma, the most aggressive form of skin cancer, is characterized by its accumulation of a large number of mutations. Although some of these alterations should be recognized as a threat by our defenses, melanomas often escape immune system surveillance. As a result, more than half of patients do not generally respond to current immunotherapies. Understanding and avoiding this phenomenon is one of the greatest challenges in oncology today.

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Utilizing Gene Expression Profiling to Avoid Unnecessary Interventions in a 72-Year-Old Woman With Melanoma

An expert discusses initial thoughts on the case, including the risk category the patient would fall into based on the characteristics of their lesion, outlines the treatment guidelines for melanoma based on their risk, and suggests the frequency of surveillance visits solely based on their traditional risk classification.

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