Microbiotica has dosed the first subject in the Phase Ib MELODY-1 clinical trial of MB097, a precision microbiome co-therapy targeting advanced melanoma.
Health Professionals
Dr Truong on Targeted Therapy vs Immunotherapy in BRAF V600–Positive Melanoma
Thach-Giao Truong, MD, medical director, Melanoma Program, Cleveland Clinic, discusses long-term findings from the phase 2 ImmunoCobiVem trial (NCT02902029) investigating early switch from targeted therapy to immunotherapy in patients with advanced BRAF V600–positive melanoma.
Melanoma with Drug Resistance: Cause Identified
Newswise — Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known as the most lethal form of skin cancer due to its high rates of metastasis and recurrence. With the global trend of aging populations, the number of melanoma patients is rapidly increasing, and it is projected that by 2040, approximately 100,000 people worldwide will die from melanoma annually. In clinical practice, melanoma is currently treated with targeted therapies that inhibit the BRAF oncogene. However, drug resistance to BRAF inhibitors develops quickly, limiting the effectiveness of these treatments.
Cell line models identify cause of melanoma with drug resistance
Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known as the most lethal form of skin cancer due to its high rates of metastasis and recurrence. With the global trend of aging populations, the number of melanoma patients is rapidly increasing, and it is projected that by 2040, approximately 100,000 people worldwide will die from melanoma annually.