The study could open the door to potential novel therapeutic targets.
Health Professionals
New immunotherapy strategy targets macrophage receptors to enhance melanoma treatment
Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study, published in the Journal for ImmunoTherapy of Cancer, shows that blocking MARCO in combination with a type of immunotherapy known as anti-CTLA4 therapy, significantly enhances tumor regression in melanoma, the deadliest form of skin cancer.
Tilsotolimod Provides No Added Benefit in Advanced Melanoma
The combination of tilsotolimod and ipilimumab does not improve response rates or survival outcomes over ipilimumab alone in patients with advanced melanoma, according to phase 3 trial results published in the Journal of Clinical Oncology.
Remote Telemedicine Tool Highly Accurate in Diagnosing Melanoma
Collecting images of suspicious-looking skin growths and sending them off-site for specialists to analyze is as accurate in identifying melanomas as having a dermatologist examine them in person, a new study showed.