A phase 1/2 trial evaluating KSQ-004EX, a novel CRISPR-engineered tumor infiltrating lymphocyte (eTIL) therapy, has dosed its first patient with an advanced solid tumor.
Health Professionals
Advanced Melanoma at Diagnosis Associated With Several Patient-Specific Factors
Patients with certain sociodemographic factors are significantly more likely to present with advanced-stage melanoma at diagnosis, including those who live farther from treatment centers, those with Medicaid or without insurance, and those from lower-income households, among other factors. These study findings were published in SKIN.
Skin cancer patients given fast-tracked access to ‘revolutionary’ vaccine trial
Source: University Hospital Southampton, April 2025 Patients with advanced melanoma are set to be fast-tracked into clinical trials of a new cancer vaccine following the expansion of a Southampton-run national…
Read More Shared Protein Link Found Between Parkinson’s and Cancer
Summary: A new study reveals that the protein alpha-synuclein, known for its role in Parkinson’s disease, also contributes to the development of melanoma by promoting excessive DNA repair and cell proliferation. While in neurons, excess alpha-synuclein leads to cell death, in melanoma cells it enables uncontrolled growth by recruiting repair proteins to DNA breaks.