Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms of skin cancer, with current therapies—including immunotherapy and targeted drugs—showing limited effectiveness. Radiotherapy is an emerging treatment for melanoma, but conventional beta-emitting radionuclide therapies have limitations due to their low energy transfer and long-range radiation, which can cause unintended damage to healthy tissues.
Of Interest
Targeted alpha therapy: Breakthrough in treating refractory skin cancer
Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms of skin cancer, with current therapies — including immunotherapy and targeted drugs — showing limited effectiveness. Radiotherapy is an emerging treatment for melanoma, but conventional beta-emitting radionuclide therapies have limitations due to their low energy transfer and long-range radiation, which can cause unintended damage to healthy tissues.
Advancing Therapies Have Improved the Prognosis of Metastatic Melanoma
Recent advancements in the melanoma treatment paradigm have drastically improved outcomes and changed the diagnosis of metastatic melanoma from a horrible prognosis to a potentially curable one. DocWire News spoke to John Fruehauf, MD, field medical director at Evolent, about how new therapies have improved the landscape of metastatic melanoma care.
Several Models Externally Validated for Sentinel Lymph Node Biopsy Positivity in Melanoma
WEDNESDAY, March 12, 2025 (HealthDay News) — In a review and meta-analysis published online March 12 in JAMA Dermatology, several risk prediction models are identified and externally validated for sentinel lymph node biopsy (SLNB) positivity in melanoma.