Melanoma, recognized as the most aggressive type of skin cancer, poses severe health risks due to its ability to metastasize, despite being less common than other skin cancers. The primary risk factor for melanoma is prolonged exposure to ultraviolet (UV) radiation, which leads to oxidative stress and inflammation in skin cells through photo-oxidative reactions.
Of Interest
Smart nanotherapy enhances immune attack on melanoma
Researchers have developed an innovative nano-immune agonist that significantly improves immunotherapy outcomes for melanoma—a highly aggressive and hard-to-treat form of skin cancer.
Liquid Biopsies Reliably Predict Immunotherapy Outcomes in Melanoma Study
Among patients with advanced melanoma treated with ipilimumab (Yervoy) and nivolumab (Opdivo), decreasing values of circulating tumor DNA (ctDNA) in tumor-informed liquid biopsies during the first 6 weeks of therapy were associated with improved survival outcomes, a recent study showed.
Melanoma in Adolescents and Young Adults: Declining Incidence, Rising Mortality
Melanoma in adolescents and young adults (AYAs) has distinct epidemiologic characteristics, with a declining incidence over the past 2 decades but an increasing trend in all-cause and cancer-specific mortality among specific populations, according to study results published in Clinics in Dermatology.