PD-L1 ligand expression demonstrates heterogeneity in both pre- and postconditions and was without direct correlation with the interactive state or TVEC response. The red line indicates no interaction (transfer efficiency of 4% or lower). Credit: JCO Oncology Advances (2025). DOI: 10.1200/OA-24-00049
Of Interest
Dr Chmielowski on the Rationale for Investigating Oncolytic Viruses in Melanoma
Bartosz Chmielowski, MD, PhD, health sciences clinical professor, medicine, Division of Hematology-Oncology, Sarcoma and Connective Tissue Medical Oncology, UCLA Health, discusses the rationale for investigating oncolytic viruses in melanoma.
Study Reveals Immune Checkpoint Inhibitor Treatment and Monitoring Practices Post-Remission
Post treatment discontinuation, most centers conduct imaging every 3 months during the first year of remission.
Recurrence, mortality rates better in nevus-associated vs. de novo acral melanoma
Five-year recurrence-free survival was 55.1% with nevus-associated acral melanoma (NAAM) vs. 42.3% with de novo acral melanoma (DNAM).