Given the limited knowledge on how indoor tanning promotes melanoma development, researchers assessed indoor tanning use in patients with melanomas in sun-exposed skin, and analyzed the link between indoor tanning exposure and clinicopathological and molecular features.
Publications
TLR9 Agent Triggers Durable Response in Metastatic Melanoma
The use of CMP-001, an intratumoral toll-like receptor 9 (TLR9) agonist, is capable of triggering durable responses when used in combination with pembrolizumab (Keytruda) for patients with PD-1 resistant metastatic melanoma according to results from a phase Ib study presented at the Society for Immunotherapy of Cancer’s 34th Annual Meeting (SITC 2019).1
Melanoma Journal Articles for October 2019
Please click on the link to see a list of melanoma journal citations that crossed the MRV desk this month.
Exogenous hormone use and cutaneous melanoma risk in women: The European Prospective Investigation into Cancer and Nutrition
Among women enrolled in the European Prospective Investigation into Cancer and Nutrition, a prospective cohort analysis started in 1992 in 10 European countries, researchers investigated the links between the use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk. A total of 334,483 women with 1,696 melanoma cases were identified over 1992–2015, including 134,758 postmenopausal women with 770 cases