This study was undertaken to determine if the level of UV damage at the site of melanomas was correlated with genetic polymorphisms.
Publications
Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies
Researchers investigated the efficacy of the tumor microenvironment-derived protein S100A8/A9 as a prognostic marker for melanoma patients, also in the setting of immunotherapy. Using a cDNA library and three independent tissue-microarrays (TMA), they analyzed S100A8/A9 gene and protein expression on melanocytic nevi, primary melanomas and metastases.
Melanoma Journal Articles for November 2019
Please click on the link to see a list of melanoma journal citations that crossed the MRV desk this month.
Association of indoor tanning exposure with age at melanoma diagnosis and BRAF V600E mutations
Given the limited knowledge on how indoor tanning promotes melanoma development, researchers assessed indoor tanning use in patients with melanomas in sun-exposed skin, and analyzed the link between indoor tanning exposure and clinicopathological and molecular features.