The FDA granted a fast track designation to ST101 for the treatment of advanced cutaneous melanoma in patients who have disease progression on or after anti-PD-1/anti-PD-L1 therapy.
Publications
Melanoma detection during routine skin checks and mortality
Melanomas diagnosed during routine skin checks were identified to be related to significantly lower all-cause mortality, but not melanoma-specific mortality, post-adjustment for patient, sociodemographic, and clinicopathologic factors.
NICE recommends monotherapy for adjuvant treatment of stage 3 melanoma
The approval follows a successful period of monitoring and patient access through the Cancer Drugs Fund.
Blood pressure and risk of cancer: a Mendelian randomization study
Previous large observational cohort studies showed higher blood pressure (BP) positively associated with cancer. We used Mendelian randomization (MR) to obtain less confounded estimates of BP on total and site-specific cancers.