Melanoma has been at the forefront of the immuno-oncology revolution, a trend that continued at the 2015 ASCO Annual Meeting.
MRV Research
Interpreting PD-L1 Status Among Key Melanoma Topics at ASCO
Key areas in the treatment of melanoma discussed at the 2015 ASCO Annual Meeting included selecting appropriate immunotherapy regimens based on PD-L1 status and improving surgical practices. OncLive sat down with Jason J. Luke, MD, assistant professor of Medicine at University of Chicago Medicine, to provide deeper insight on both topics.
TCGA Classifies Four Melanoma Subtype
New data out of the Cancer Genome Atlas (TCGA) suggests that cutaneous melanomas can be classified into four categories based on the pattern of the most prevalent significantly mutated genes: BRAF, RAS, NF1, and Triple-WT.
Certain Notch Pathway Genes Predict Survival in Cutaneous Melanoma
Cutaneous melanoma disease-specific survival may be predicted by the SNPs in Notch pathway genes, according to a study published online in Cancer Epidemiology, Biomarkers & Prevention.