Ultrasmall gold nanoparticles (less 3 nm in diameter) are a promising therapeutic platform for cancer treatment due to their ability to accumulate in the nuclei of cells. Once inside cells, the nanoparticles can effectively deliver anticancer agents and simultaneously be used in radiotherapy for dose enhancement. However, achieving accumulation and retention of nanoparticles in tumours from systemic administration remains a challenge.
MRV Research
Viagra Does Not Cause Melanoma, According to Study
A thorough assessment of over 20,000 medical records revealed that erectile dysfunction drugs like Viagra do not cause melanoma despite the elevated risk for the disease among those who use such drugs. The report was published in the Journal of the American Medical Association.
Gene Expression May Help Predict Sentinel Lymph Node Positivity in Melanoma Patients
By exploring gene expression variables in addition to clinicopathologic variables, researchers were able to better predict which patients with melanoma would have sentinel lymph node (SLN) biopsy positivity, according to the results of a study published in the Journal of Clinical Oncology.
FIGHTING MELANOMA FROM THE INSIDE
IN the summer of 2004, few of the patients enrolling in Study 020 would have been thinking about sunny weather and days on the beach. Looming larger in their minds would have been the fact that within a year, three in every four of them were likely to be dead. All of them, from teenagers to seniors, had late-stage melanoma that chemotherapy could not help, and for which surgery could not be used. This trial was quite literally their last hope.