In a new study entitled “Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity” scientists at The Francis Crick Institute discovered that administrating aspirin (or other COX inhibitors) together with immunotherapies boosts the immune response against tumor cells. The study was published in the journal Cell.
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Deadly melanoma discovery supports immunotherapy treatment for cancer
Immunotherapy has received a boost as a treatment approach for cancer, in light of research carried out by a group of international scientists led by a team at the University of California-San Francisco. A rare and deadly form of skin cancer, known as desmoplastic melanoma (DM), has been found to contain more gene mutations than any other cancer so far.
Desmoplasmic melanoma may possess unprecedented burden of gene mutations, say UCSF scientists
A rare, deadly form of skin cancer known as desmoplasmic melanoma (DM) may possess the highest burden of gene mutations of any cancer, suggesting that immunotherapy may be a promising approach for treatment, according to an international team led by UC San Francisco scientists. One of these mutations, never before observed in any cancer, may shield nascent DM tumors from destruction by the immune system and allow further mutations to develop.
Immune perturbations may increase melanoma risk among certain non-Hodgkin’s lymphoma survivors
Certain chemotherapeutic agents and immune-related medical conditions appeared to contribute to increased melanoma risk among older survivors of a specific non-Hodgkin’s lymphoma subtype, according to results of a retrospective study.