Children are not small adults, even when it comes to the way they present with melanoma.
Kelly M. Cordoro, M.D., and colleagues recently reported on how common it is for children to present atypically with melanoma.
Children are not small adults, even when it comes to the way they present with melanoma.
Kelly M. Cordoro, M.D., and colleagues recently reported on how common it is for children to present atypically with melanoma.
Read Dr. Constance Brinckerhoff interview with Medical research.com on how Melanoma Cells Alter Their Environment To Promote Progression
The genetic mutation BRAFV600E secretes a protein that promotes the growth of melanoma tumor cells and modify the network of normal cells around the tumor to support the disease’s progression, according to a new paper.
Stage IV melanoma is an aggressive malignancy with a median survival shorter than 1 year. The identification of activating mutations in a component of the mitogen activated protein kinase (MAPK) pathway called BRAF in 40% to 60% of melanomas has allowed for the development of efficacious therapies that inhibit the activity of the pathway.