Researchers from the Sanford-Burnham Medical Research Institute discovered that without a source of glutamine (one of the amino acids forming proteins) melanoma cells stop proliferating and die.
MRV Research
Scientists discover previously unidentified gene key to melanoma progression
Findings at California Pacific Medical Center Research Institute shed new light on how deadly skin cancer develops, and suggest novel strategies for preventing resistance to therapy.
Decreased RNA-Editing Promotes Melanoma Progression
A new study entitled “Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis” showed how lack of RNA-editing, a key cellular process whereby RNA nucleotides are modified, contributes to tumor growth and cancer progression in melanoma by increasing the expression of an oncogenic miRNA. The study was published in the February edition of the journal Nature Cell Biology.
MD Anderson Studies Skin Cancer Patients Resistant to Leading Therapy
Powerful drugs known as BRAF-inhibitors have been crucial for melanoma patients, saving lives through their ability to turn off the BRAF protein’s power to spur cancer cell growth.