Researchers from the UNC Lineberger Comprehensive Cancer Center analyzed hundreds of melanoma samples to find out if two genetic mutations more commonly found in melanoma tumors were associated with lower survival rates in patients.
MRV Research
UQDI reveals that Anisina drug can kill melanoma cells
US-Australian drug discovery company, Novogen today announced that studies conducted at The University of Queensland Diamantina Institute (UQDI) revealed that experimental drug, Anisina, killed melanoma cells irrespective of their mutational status.
Epigenomic changes play an important role during the progression of melanoma
KU Leuven researchers have zeroed in on what makes cancer cells in melanoma so aggressive. They also succeeded in taming the effect in cell cultures. Melanoma, a type of skin cancer, is notoriously quick to metastasize and responds poorly to existing cancer treatments. In their study, published in Nature Communications, the researchers report a significant step forward in the characterization and potential treatment of melanoma.
Combining Autophagy Inhibition With Dabrafenib May Provide Benefit for Melanoma Patients
The removal of a gene involved in the cellular self-cannibalization process of autophagy could provide therapeutic benefit to patients with melanoma. Investigators at Rutgers Cancer Institute of New Jersey now have demonstrated autophagy inhibition may be of therapeutic value by augmenting the antitumor activity of BRAF inhibitors.