In a new study entitled “CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity,” researchers revealed that CXCR3 signaling promotes wild-type BRAF melanoma progression by inducing invasive and metastatic characteristics. The study was published in the open-access journal PLOS One.
MRV Research
Melanoma’s ‘safe haven’ targeted for shut-down
Melanoma cells become drug resistant by using surrounding healthy cells to provide a ‘safe haven’ from treatment, according to new research published in Cancer Cell today.
Immunotherapy Innovator Jedd Wolchok Honored
Before the Internet and global interconnectedness, advancements in science and medicine were usually slow and incremental, with research and findings conducted by solo researchers and shared over time.
Plasmid IL-12 electroporation shows promise in melanoma
Intratumoral plasmid interleukin-12 electroporation was associated with local necrosis and increased tumor infiltrating lymphocytes and can lead to systemic tumor regression in melanoma, according to study results presented at the HemOnc Today Melanoma and Cutaneous Malignancies meeting.