Melanoma News

Mount Sinai Researchers Discover How Melanoma May Spread to the Brain

Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in the latest issue of Molecular Cell, highlights the role of a group of proteins called the PBAF chromatin remodeling complex in keeping melanoma from getting worse.

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Genetic Ancestry and Immunotherapy Response in High-Risk Melanoma

Ahmad Tarhini, MD, PhD, professor and senior member in cutaneous oncology and immunology at Moffitt Cancer Center, discusses inherited genetic variations and genetic ancestry, particularly for patients with high-risk melanoma. With a longstanding focus on improving immunotherapy outcomes and mitigating treatment-related toxicities, Tarhini and his team aim to bridge critical knowledge gaps in precision oncology through this work.

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