The individualized neoantigen therapy mRNA-4157 (V940), combined with pembrolizumab (Keytruda), improved relapse-free survival (RFS) and distant metastasis-free survival (DMFS) compared with pembrolizumab alone in patients with high-risk resected melanoma, according to findings from the phase 2 KEYNOTE-942 trial (NCT03897881) presented at the 2023 European Society for Medical Oncology Congress (ESMO).
2023
Genetic Plot Twist: New Discovery Challenges Our Understanding of Skin Tone and Ancestry
Geneticists have conducted research to understand the genetic origins of skin pigmentation variations among different ethnicities, revealing that genes associated with East Asian and Native American ancestry are responsible for their lighter skin tones.
More GPs needed to keep melanoma care equitable across Queensland
While access to invasive melanoma health care is fairly equitable across Queensland, people in regional areas are relying more on public hospitals for treatment rather than GPs or skin cancer specialists.
Rise in skin cancer cases underscores importance of early detection using machine learning
In a recent review published in the Life Journal, a group of authors reviewed image-processing techniques in machine learning (ML) for skin cancer detection using clinical images, evaluating their efficacy, available datasets, and challenges.