Archive | Publications

FDA Approves Adjuvant Pembrolizumab in Stage III Melanoma

Source: OncLive, March 2019 The FDA has approved the PD-1 inhibitor pembrolizumab (Keytruda) for the adjuvant treatment of patients with high-risk stage III melanoma with lymph node involvement following complete resection.1 This is the first anti–PD-1 therapy evaluated in the adjuvant setting across patients with stage IIIA, stage IIIB, and stage IIIC melanoma. The approval is […]

Read the full story

Posted in Melanoma News, Publications, Scientific Publications

Early melanoma nodal positivity and biopsy rates before and after implementation of the 7th edition of the AJCC Cancer Staging Manual

Source: MDLinx, March 2019 In this cross-sectional study of 86,846 patients diagnosed before the seventh edition of the AJCC Cancer Staging Manual (AJCC 7) (2004-2009) and of 54,434 patients diagnosed after AJCC 7 (2010-2013), researchers assessed the change in staging criteria and the distribution of thin melanomas requiring nodal and nodal positivity rates seen with […]

Read the full story

Posted in Melanoma News, Health Professionals, Of Interest, Publications, Scientific Publications

Dietary factors tied to melanoma-immunotherapy response

Source: MDLinx, March 2019 In a small study of melanoma patients, a high-fiber diet was associated with higher gut microbiome diversity and better response to immunotherapy, while probiotic therapy had the opposite effect. “There’s a perception that taking probiotics improves gut health, but our results, although early, suggest that may not be the case for […]

Read the full story

Posted in Melanoma News, Publications, Scientific Publications

Eosinophil-cationic protein – A novel liquid prognostic biomarker in melanoma

Source: MDLinx, March 2019 In view of the observation that eosinophil cationic protein (ECP) mediates anticancer effects, such as tissue remodelling and cytotoxic activity, researchers examined the prognostic value of this marker in metastatic melanoma. They studied serum of 56 melanoma patients, collected at the time of diagnosis of metastatic disease, for measures of ECP […]

Read the full story

Posted in Melanoma News, Publications, Scientific Publications