Archive | Publications

Toxicity profile of treatment with PD-1 inhibitors for lung cancer, melanoma and renal cell carcinoma: A real-world Brazilian study

Immunotherapy revolutionized cancer care in the last decade and, notably among its tools, the programmed cell death protein-1 (PD-1) inhibitors.

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Posted in Melanoma News, Publications, Scientific Publications

Second-Line Treatment With Apatinib in Patients with Recurrent or Refractory Melanoma

According to Shumin Yuan and colleagues from the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital in Zhengzhou, China, metastatic malignant melanoma is associated with very poor prognosis, partly due to resistance against conventional chemotherapies.

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Posted in Melanoma News, Publications, Scientific Publications

Does the morphology of cutaneous melanoma help explain the international differences in survival? Results from 1,578,482 adults diagnosed during 2000-2014 in 59 countries (CONCORD-3)

BACKGROUND: CONCORD-3 highlighted wide disparities in population-based 5-year net survival during 2000-2014. Clinical evidence suggests marked international differences in the proportion of lethal acral and nodular subtypes.

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Posted in Melanoma News, Publications, Scientific Publications

FDA Grants Fast Track Designation to 7HP349 for Anti-PD-1 Metastatic Melanoma

Fast track designation has been granted to 7HP349, in combination with a CTLA-4 inhibitor for the treatment of patients with unresectable or metastatic malignant melanoma following treatment failure with a PD-1 inhibitor.

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Posted in Melanoma News, Regulatory, Publications