Therapy for the elderly with melanoma may be affected by findings that aged tumor cells in melanoma behave differently than younger tumor cells. The microenvironment, particularly dermal fibroblast cells, were found to have age-related changes that could drive melanoma metastasis and its response to targeted therapy.
MRV Research
Sun Exposure Beneficial Despite the Risk of Melanoma
Though sunbathers are at an increased risk of developing skin cancer, women who sunbathe are likely to live longer than those who avoid the sun. Active sun exposure among women with habits of time in the sun was linked to a decrease in cardiovascular disease and a decrease in mortality from noncancer and noncardiovascular causes compared with those who avoid sun exposure.
Nivolumab Monotherapy Induces Durable, Long-term Survival in Advanced Melanoma
After 5 years of follow-up, 34% of patients with advanced melanoma who participated in a phase 1 clinical trial are still alive after receiving nivolumab treatment, a study presented at the American Academy for Cancer Research (AACR) Annual Meeting 2016 has shown.
Preeminent experts provide roadmap for future melanoma research
Recently the Melanoma Research Foundation (MRF) convened a summit of internationally-renowned melanoma experts for an in-depth discussion on the current understanding of, and future recommendations for, melanoma research. The result of the comprehensive process is a new white paper entitled, “The State of Melanoma: Challenges and Opportunities," published in the latest edition of the premier melanoma journal, Pigment Cell & Melanoma Research. In the white paper, the melanoma experts, including researchers, clinicians and patient advocates, identify the critical issues related to prevention, detection and early diagnosis, dormancy, metastasis and therapy.