Tumor characteristics found to differ for melanomas in children, teens and young adults

Source: Medical Xpress, November 2024

Tumor characteristics differ significantly among pediatric and adolescent and young adult (AYA) patients with melanoma, with decreasing incidence rates seen among young patients with cutaneous melanoma, according to a study published online Nov. 15 in the Journal of the American Academy of Dermatology.

Bianca E. Ituarte, from the University of Nebraska Medical Center in Omaha, and colleagues examined the incidence trends and melanoma presentations based on age, sex, race, and ethnicity using a large cohort of diagnoses from 1997 to 2020 in a retrospective cohort study completed using the National Childhood Cancer Registry for pediatric and AYA patients.

The researchers found that for pediatric and AYA patients, the incidence rates were 1.74 and 62.05 per 1 million person-years, respectively. Overall, 62.3 percent of the cohort was female. Non-Hispanic White patients accounted for 87.5 percent of all diagnoses, with the incidence rates of melanoma significantly higher compared with all other racial and ethnic groups in pediatric and AYA patients.

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