The worse survival outcomes reported for melanoma patients having sentinel node biopsy after lymphoscintigraphy the previous day do not appear to be due to overnight migration of Tc99m-nanocolloid tracer
Source: MDLinx, March 2021
Patients having sentinel node (SN) biopsy for melanoma the day after lymphoscintigraphy using Tc99m-nanocolloid are reported to have worse survival outcome than that of patients having lymphoscintigraphy and SN biopsy on the same day.
Overnight migration of the tracer from SNs to 2nd-tier nodes occurs, causing failure to remove true SNs, might be a possible explanation for aforementioned condition.
