Study uncovers how B cells react to skin cancer

Source: Medical Xpress, June 2023

A new study that sheds light on how B cells react to skin cancer cells could pave the way for innovative therapy design.

The study, published today in Nature Communications and led by researchers from King’s College London, reveals that antibody-producing B cells in patients may be defective in responding to the most aggressive skin cancer, melanoma.

Antibodies are produced by B cells, a type of white blood cell, and are made to prevent and help fight infections. However, there is limited understanding about how B cells are prompted to respond to melanoma and why the antibodies they make are not effective.