Spindle cell melanoma

Source: DermNet  NZ, January 2020

Spindle cell melanoma is a rare histological variant of melanoma, characterised by the presence of spindle-shaped melanocytes [1]. On microscopy, it is often mistaken for other skin and soft tissue cancers with spindle cell morphologies.

Desmoplastic melanoma is a variant of spindle cell melanoma where there are varying proportions of spindle cells and desmoplastic cells present in the histology.

Further studies are needed to clarify the clinical manifestations, risk factors, treatment management, and prognosis of spindle cell melanoma.