Smoking Tied to Increased Mortality From Early-Stage Melanoma

Source: MEDPAGE TODAY, February 2024

Patients with clinically localized primary cutaneous melanoma who smoked cigarettes at the time of diagnosis had an increased risk of melanoma-associated mortality, a cohort study showed.

In a post hoc analysis of data derived from two randomized trials involving more than 6,000 patients, current smoking was associated with a 48% greater risk of melanoma-associated death compared with never smoking (HR 1.48, 95% CI 1.26-1.75, P<0.001), reported Katherine M. Jackson, MD, of Saint John’s

Cancer Institute in Santa Monica, California, and colleagues.
Notably, former smoking showed no association (HR 1.03, 95% CI 0.89-1.20, P=0.68), they detailed in JAMA Network Open
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