‘Shocking’ results reveal imaging can detect early response to immunotherapy for melanoma
Source: Healio, January 2024
Key takeaways:
- FDG PET/CT imaging detected metabolic changes in patients with advanced melanoma beginning immunotherapy in the first week.
- Detection of metabolic changes correlated with longer PFS.
Metabolic changes can be identified in patients with advanced melanoma by imaging tumors within 1 week of beginning immunotherapy, according to a study published in Clinical Cancer Research.
Patients who had metabolic changes detected with an 18F-fluorodeoxyglucose (FDG) PET/CT had a 100% overall response rate compared with 38% for those that did not, and a median PFS nearly 3 years longer.