Scientists uncover how incurable skin cancer resists treatment at the end of life

Source: Cancer Research Uk, March 2023

The results of new research have revealed how some skin cancers stop responding to treatment at the end of life.

As part of the Cancer Research UK-funded PEACE study, 14 patients with advanced melanoma skin cancer consented to have their tumours analysed after their death.

Those samples were analysed using advanced genome sequencing techniques to map out the final stages of their cancer. The analysis uncovered changes to the order, structure and number of copies of tumour DNA that could allow melanoma to develop resistance to treatment.

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