Scientists Reveal How Incurable Skin Cancer Resists Treatment

Source: Scitech Daily, April 2023

Researchers have discovered the reason why some skin cancers cease to respond to treatment toward the end of the patient’s life.

A comprehensive study of 14 individuals who passed away from untreatable melanoma has uncovered that alterations in the arrangement, composition, and duplication of tumor DNA can lead to resistance to treatment in some skin cancers. These modifications also shed light on how melanoma can proliferate to other areas of the body.

Scientists have discovered that alterations in the tumor DNA, such as changes in order, structure, and copy numbers, can cause some skin cancers to resist treatment and spread to other body parts. The findings could help develop new treatments that increase the life expectancy of patients with advanced cancer.