Science Fiction Becomes Fact: Neoantigen Therapy in Melanoma

Source: Medscape, April 2024

This transcript has been edited for clarity.

Hello. I’m David Kerr, professor of cancer medicine at University of Oxford. I’d like to talk to you today about a study that’s been published recently in The Lancet that is science fiction becoming science fact.

The title of the paper is “Individualised Neoantigen Therapy mRNA-4157 (V940) Plus Pembrolizumab Versus Pembrolizumab Monotherapy in Resected Melanoma (KEYNOTE-942): A Randomised, Phase 2b Study." I’ll talk more about the design in a moment.

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