Risk of Leptomeningeal Metastasis in Melanoma Linked to Anatomic, Surgical Factors

 Source: Cancer Therapy Advisor, February 2022

Sucharita Mistry, PhD

Among patients with melanoma brain metastases (MBM), surgical intervention was not the only risk factor for developing leptomeningeal disease (LMD), according to a retrospective study published in Neuro-Oncology.

The study revealed that anatomical factors such as dural-based and intraventricular metastasis, as well as metastasis bordering a ventricle or cerebrospinal fluid (CSF) cistern, were associated with an increased risk of developing LMD.

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