Researchers Establish, Validate Prognostic Model for Uveal Melanoma
Source: AJMC, May 2022
The model consists of 3 metabolism-related genes—carbonic anhydrase 12, acyl-CoA synthetase long-chain family member 3, and synaptojanin 2— that the researchers said could potentially be used as biomarkers and treatment targets in the disease.
Authors of a new study have created and validated a prognostic model they say could accurately predict prognosis of uveal melanoma (UM), a disease that carries a high mortality rate and overall survival (OS) time of approximately 1 year.
The group underscored the utility of their metabolic signature-based model, which they say could also allow for the identification of high-risk patients who may benefit from more frequent follow-up strategies.